Какао, однако, надо пить :-)
From: Андрей Петров <mister.ap20***@y*****.ru>
To: ""science.news.bessmertie"" <privatmemb***@y*****.com>
Sent: Thursday, January 31, 2013 1:26 AM
Subject: Re: инсулин; магний-глюкоза
Очень интересно!
Как будем магний добывать?
30.01.2013 2:39, "Stas AV" пишет:
> http://www.lef.org/newsletter/2013/0129_Meta-Analysis-Links-Increased-Magnesium-Intake-With-Fasting-Glucose-And-Insulin-Reductions.htm
> Meta-analysis links increased magnesium intake with fasting glucose and
> insulin reductions
>
> Tuesday, January 29, 2013. The results of a meta-analysis published online
> on January 23, 2013 in the Journal of Nutrition reveal an association
> between diets that include higher amounts of magnesium and lower levels of
> fasting glucose and insulin.
>
> American and European researchers sought to determine the influence of
> genetic variations associated with glycemic traits or magnesium metabolism
> on fasting glucose and insulin levels, which are elevated in metabolic
> syndrome and type 2 diabetes. "Evidence from cross-sectional and
> longitudinal observational studies suggests that diets higher in magnesium
> are associated with reduced risk of insulin resistance and type 2 diabetes,
> whereas in intervention studies, supplemental magnesium improves measures of
> glucose and insulin metabolism in generally healthy adults, as well as in
> those with insulin resistance and type 2 diabetes," Adela Hruby and
> colleagues write. "However, little is known about potential interaction
> between magnesium intake and genetic variability on glycemic traits, in
> which genetic variants related to either magnesium transport and homeostasis
> or glucose and insulin metabolism may modify the pathways through which
> magnesium exerts its effects."
>
> The researchers analyzed data from up to 52,684 nondiabetic men and women
> who participated in 15 studies included in the Cohorts for Heart and Aging
> Research in Genomic Epidemiology (CHARGE) Consortium. Dietary questionnaire
> or interview responses, or food diary entries were analyzed for magnesium
> content from food and beverages. Participants were genotyped for up to 25
> single nucleotide polymorphisms related to fasting glucose, insulin or
> magnesium.
>
> Average magnesium intake ranged from 224.7 milligrams to 479.7 milligrams
> per day. Reductions in both fasting glucose and fasting insulin were
> observed in association with increased magnesium. While a nominal
> association was found between one of the genetic variants examined in this
> study and fasting glucose and two variants showed nominal interactions with
> magnesium intake on fasting glucose and fasting insulin, no significant
> effects for the variations were observed.
>
> "To our knowledge, this is one of the largest observational studies to
> investigate magnesium intake's associations with fasting glucose and fasting
> insulin, and it is the largest meta-analysis investigating interactions
> between magnesium intake and risk loci on fasting glucose and fasting
> insulin," the authors announce.
>
> "Our results indicate that higher dietary magnesium intake is inversely
> associated with fasting glucose and fasting insulin in individuals free of
> diabetes, generally irrespective of genetic variation at glycemia- and
> magnesium-related loci investigated," they conclude.
>
